Is Cannabis Any Good for Chronic Pain Relief?

The Internal Association for the Study of Pain issued a definition that describes pain as “an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage.”

However, if we were to put it in simple terms: it‘s simply an uncomfortable sensation that tells you something is wrong with your body.

When people talk about pain, there are so many inclinations to what they could mean. Although using conventional treatments have helped some, they often lead to certain side-effects. Case in point: opioids.

This forced people to look for other alternatives that could potentially provide chronic pain relief without any side-effects.

The fact that medical marijuana could meet this need piqued the interest of people across the globe, and with several testimonials vying for the efficacy of cannabis for pain relief, the popularity is only growing.

Cannabis and Chronic Pain: How Can it Help?

The cannabis flower has two main cannabinoid compounds namely, THC and CBD. Both these compounds work together, as well as separately, to reduce pain by acting on the CB1 and CB2 receptors found in the central nervous system.

These receptors have the ability to influence and regulate – partly – the feelings of pain in the primary four modules that include acute, chronic, cancer, and neuropathic.

Additionally, other elements found in the cannabis plant like terpenes linalool and myrcene, and CBC also have pain-relieving properties.

When all these compounds work together as one, it enhances their ability to fight pain and reduce its symptoms because of the Entourage Effect.

Cannabis and Chronic Pain: What Does Research Say?

Experts conducted a study involving animals where they used topical CBD oil for relieving pain and inflammation. Another study found evidence that highlighted how CBD helped to lower neuropathic pain by suppressing chronic inflammation.

And not only CBD, but even THC has also been found to potentially alleviate symptoms of neuropathic pain and chronic pain. THC works as a partial CB1 receptor agonist that experts found could impact the glutamatergic, dopaminergic, and serotonergic systems.

Cannabis and Chronic Pain: What are the Best Cannabis Strains for Pain Control

Now that we’ve spoken about the efficacy of marijuana for pain, let’s also discuss cannabis Sativa strain products that could help with pain management.


This cannabis strain can work effectively to provide pain relief without making your mind foggy, which is because of its high non-psychoactive CBD content that, as discussed above, can reduce pain symptoms.

Harlequin is known to alleviate the pain associated with joint pain and stiffness as well – whether mild or chronic. In a similar manner, it can be useful for fibromyalgia and neuralgic pain patients. 

Its terpene profile includes pain relief elements like myrcene, pinene, and caryophyllene that can help you relax without sedation and to lower pain without intoxication.


ACDC combines the power of CBD and THC that makes it a very effective painkiller. It can also be useful for people suffering from anxiety too.

This Sativa-dominant phenotype has powerful terpenes like caryophyllene, myrcene, linalool, pinene, and limonene that synergize to help lower pain and inflammation. If you prefer a fruity and sweet taste, this could be the perfect option for you.

Blackberry Kush

Blackberry Kush is a THC-dominant Indica hybrid marijuana strain that creates a state of euphoria and simultaneously manages pain symptoms. Its sweet berry flavor and long-lasting Indica high is also another reason why it’s so popular.

Although it’s mostly renowned for natural pain relief because of its powerful sedative effects, it can also be used by patients of insomnia, anorexia, and nausea. 

Blue Widow

Having a robust terpene profile of myrcene, caryophyllene, and limonene with a rich CBD and THC content, Blue Widow is one of the best hybrid marijuana strains for chronic pain relief primarily because of its anti-inflammatory benefits. 

Keep in mind that even though Blue Widow’s stress and pain-relieving properties stem from its parent strain, White Widow, both are different strains and shouldn’t be considered the same. The former has a unique flavor with a diesel-like sour taste and hints of Blueberry. 

Northern Lights

This cannabis strain has a 16% THC dominance and less than 1% CBD and can instantly help you relax thanks to its incredible terpene profile that includes caryophyllene, myrcene, and limonene.

A Sativa-dominant hybrid, with high levels of THC, Blue Dream is thought to be one of the best options for medical issues like joint pain. You can also experience mild euphoria and relaxing benefits through this strain. 

Blue Dream

Blue Dream has nearly 20% THC that gives it the ability to combat different types of aches and pains. Its terpene profile shows high levels of pinene, caryophyllene, and myrcene – each of which has pain and inflammation controlling properties. 

This cannabis strain can relax your body using subtle cerebral stimulation. However, you don’t need to worry about any heavy sedative effects upon consumption. 

Takeaway Thoughts

Although we cannot really claim cannabis to be an alternative treatment for chronic pain as more evidence is required, there’s still denying the potential that this element has for the same. 

With the growing popularity of cannabis and especially CBD, governments have started relaxing strict laws and sanctioning research to explore the efficacy of this compound and its medical benefits. Surely within a couple of years, the results will be clearer. 

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